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Ro 5212773

CAS No. 1110781-88-8

Ro 5212773( EPPTB | Epptb | Ro 5212773 )

Catalog No. M28628 CAS No. 1110781-88-8

EPPTB is a selective TAAR1 antagonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Ro 5212773
  • Note
    Research use only, not for human use.
  • Brief Description
    EPPTB is a selective TAAR1 antagonist.
  • Description
    EPPTB is a selective TAAR1 antagonist.(In Vivo):EPPTB prevents the reduction of the firing frequency of DA neurons induced by p-tyramine (p-tyr), a nonselective TAAR1 agonist. the EPPTB effects were absent in Taar1 knockout mice, ruling out off-target effects.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    EPPTB | Epptb | Ro 5212773
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    EGFR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1110781-88-8
  • Formula Weight
    378.39
  • Molecular Formula
    C20H21F3N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (264.28 mM)
  • SMILES
    CCOc1cccc(NC(c(cc2)cc(C(F)(F)F)c2N2CCCC2)=O)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.John Emmerson Campbell, et al. Inhibitors of mutant forms of egfr. Patent WO2021133809A1.
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